Practical Approach to Abnormal Liver Enzymes in Patients with Inflammatory Bowel Disease

Authors

  • Davide De Marco, MDCM Division of Gastroenterology and Hepatology, McGill University, Montreal, QC
  • Amine Benmassaoud, MDCM, MSc, FRCPC Division of Gastroenterology and Hepatology, McGill University, Montreal, QC

DOI:

https://doi.org/10.58931/cibdt.2023.1317

Abstract

Inflammatory Bowel Diseases (IBD) are chronic inflammatory conditions that can impact organ systems beyond the gastrointestinal tract. Extraintestinal manifestations (EIMs) of IBDs are common and can occur at any stage of the disease. While EIMS most commonly involve the musculoskeletal system, up to 35% of individuals with IBD exhibit hepatobiliary involvement at some point during the course of their disease, often independently of disease activity. Chronic hepatobiliary diseases are noted in 5% of patients with IBD. These diseases manifest with indicative symptoms, abnormal liver biochemistry tests, or radiological abnormalities. This review provides a comprehensive outline and approach to abnormal liver enzymes in individuals with IBD.

Author Biographies

Davide De Marco, MDCM, Division of Gastroenterology and Hepatology, McGill University, Montreal, QC

Dr. Davide De Marco is a fourth-year gastroenterology and hepatology resident at McGill University. He completed his medical school training at McGill University in 2020 and his Internal Medicine residency at McGill University in 2023. He has a wide range of clinical interests in gastroenterology including inflammatory bowel diseases and hepatology.

Amine Benmassaoud, MDCM, MSc, FRCPC, Division of Gastroenterology and Hepatology, McGill University, Montreal, QC

Dr. Amine Benmassaoud completed his medical training and specialty training in Gastroenterology at McGill University. He then pursued an advanced fellowship in hepatology at the Sheila Sherlock Liver Centre, Royal Free Hospital, London England thanks to the support of the Canadian Association for the Study of the Liver Clinical Fellowship award. He recently completed his Master’s in Experimental Medicine at McGill University. He is currently an assistant professor of medicine, and member of the Division of Gastroenterology and Hepatology at McGill University Health Centre in Montreal. As an early career clinician-investigator, his special interest is the evaluation and management of portal hypertension.

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2023-10-30

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De Marco D, Benmassaoud A. Practical Approach to Abnormal Liver Enzymes in Patients with Inflammatory Bowel Disease. Can IBD Today [Internet]. 2023 Oct. 30 [cited 2024 May 19];1(3):14–20. Available from: https://canadianibdtoday.com/article/view/1-3-de_marco_benmassaoud

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